Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep9 | Adrenal and Cardiovascular Endocrinology | ECE2020

Persistent transcriptional disruption and histone mark modifications on visceral adipose tissue after remission of hypercortisolism

García-Eguren Guillermo , Gonzalez Mar , Vizan Pedro , Giro Oriol , Beyhart Arturo , Mora Mireia , Halperin Irene , Enseñat Joaquim , Vidal Oscar , Carmona Francisco , DiCroce Luciano , Hanzu Felicia

Introduction: Chronic hypercortisolemia during Cushing Syndrome (CS) determines significant changes in the plasticity and function of metabolic tissues like visceral adipose tissue (VAT). Persistence of alterations in VAT function after CS remission is under debate, as data of clinical studies is not consistent due to confounder factors and limited availability of VAT. Animal model of reversible CS presents long-term alterations on VAT after remission. We investigate VAT alter...